Laboratory Setup

Droplet-based high-throughput screening has never been easier

Postek et al. nicely demonstrated an automated high-throughput screening for MIC determination of an antibiotic in nanolitre droplets for different E.coli concentrations. Read on »

The taste of precision

A new versatile computer-controlled gustometer has recently been described Andersen et al. The device was built to match the specific needs of scientists running behavioral, electrophysiologal, and hemodynamic investigations. The setup mainly consists of several low-pressure neMESYS syringe pumps for dosing of liquid taste solutions directly onto the participants’ tongues. Read on »

Self-immobilizing fusion enzymes for compartmentalized biocatalysis

In a recent publication, Peschke et al. successfully realized microfluidic biocatalytic cascades in a compartmentalized microfluidic chip with excellent stereoselectivities. In the experimental set-up, different substrates and cofactors solutions were placed in neMESYS low pressure syringe pumps and perfused through a four-channel PMMA microchip, which is loaded with enzymes immobilized on magnetic beads at a very low flow rate of 1 µl/min. Read on »

Selective local lysis and sampling of biological samples

In their scientific article report, Kashyap et al. from the team of Dr. Govind Kaigala at IBM Research Zurich describes a new method for local lysis of living adherent cells within a microfluidic probe for genomic and transcription profiling. Read on »

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